The invention relates to novel bispecific antigen binding molecules, comprising (a) at least one antigen binding domain capable of specific binding to CD40, and (b) at least one antigen binding domain capable of specific binding to a target cell antigen, in particular Fibroblast Activation Protein (FAP), and to methods of producing these molecules and to methods of using the same.本發明係關於新穎雙特異性抗原結合分子,其包括(a)至少一個能夠特異性結合至CD40之抗原結合結構域,及(b)至少一個能夠特異性結合至靶細胞抗原(特別是纖維母細胞活化蛋白(Fibroblast Activation Protein;FAP))之抗原結合結構域;及本發明係關於產生該等分子之方法及使用該等分子之方法。