A device for controlling acquisition of a signal representing a physiological measurement on a living being comprises: an input (102) for receiving the signal in digital form, wherein the signal has been acquired by means of at least one electrode (122; 202) without galvanic contact between the electrode (122; 202) and the living being and has been processed by circuitry (120; 206) for acquisition of the signal in analog domain to refine the signal before the signal is converted from analog to digital domain; an adaptation decision module (106), being configured to determine whether at least one measure of signal quality indicates that an adaptation of said circuitry (120; 206) for acquisition of the signal in analog domain is beneficial for the robustness of the system and/or the quality of the obtained signals; wherein the adaptation decision module (106), is arranged to output a control signal for controlling a parameter affecting amplifier saturation in processing of the signal by said circuitry (120; 206).