Cardiac glycosides to reduce pulmonary exacerbations and other adverse events in cystic fibrosis and other related disorders

• 收藏
• 分享

专利权人:

Bette Pollard

发明人:

Bette Pollard

申请号：

US14998339

公开号：

US20180064730A1

申请日:

2016.01.05

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A small molecule inhibitor for treating a disorder in mammals, wherein the disorder is characterized by high levels of inflammatory components. In a preferred embodiment, the inhibitor comprises cardiac glycosides, also known as cardiac cardenolides. In one example, the drug digitoxin is used to treat the disorder cystic fibrosis. The compounds and methods of the invention are particularly effective for treating cystic fibrosis, a disorder or condition characterized by high levels of inflammation and IL-8.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/