A portable ejection and injection device has a cylinder, a piston member and a pushing rod. The cylinder includes an ejection nozzle at its tip portion and a filling chamber to contain a liquid medicine or a lubricant. The piston member is supported within the cylinder and seals the liquid medicine or the lubricant filled in the filling chamber. The pushing rod is to be inserted into the cylinder, and formed integrally with or separately from the piston member. The cylinder and the piston member are pushed inward to eject the liquid medicine or the lubricant out and inject it in directly or by air pressure produced in the cylinder. With the portable ejection and injection device, a liquid medicine or a lubricant may be ejected to the genital area of a woman or the anus of a person to clean such a area or directly injected in it as required.