PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2 - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER

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专利权人:

NUCANA BIOMED LIMITED

发明人:

MCGUIGAN, CHRISTOPHER,BALZARINI, JAN,SLUSARCYZK, MAGDALENA,GONCZY, BLANKA,MURZIANI, PAOLA

申请号：

SG2013062823

公开号：

SG192841A1

申请日:

2012.02.29

申请国别(地区):

SG

年份:

2013

代理人:

摘要：

Phosphoramidate derivatives of 5-fluoro-2-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside transporter proteins and/or with nucleoside kinase-deficient cells and/or with mycoplasma-infected cells and/or with cells with a raised level of thymidylate synthase.

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中国工程科技知识中心

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http://www.ckcest.cn/home/