PROBLEM TO BE SOLVED: To improve rotation transmitting performance to a distal side and piercing performance in an affected part, with narrowing of a core wire by two-layer structure in the medical guide wire including an inner/outer double-layer coil structure disposed at a distal side of a core wire.SOLUTION: A core-wire distal end 2B includes a concatenated truncated-cone body 26 formed by concatenating first and second truncated-cone bodies 26A and 26B. An out diameter ratio of a lage diameter part to a small diameter part of the concatenated truncated-cone body 26 joined with an inner coil 4 is formed higher than an outer diameter ratio of a rear end side to a tip end side of the inner coil 4 and an outer diameter ratio of the rear end side to the tip end side of the outer coil 3. In the rotation operation, this configuration decreases a rotation angle of a proximal side and increases a torsion moment to the distal side so as to improve the piercing performance in the obstructed affected area.COPYRIGHT: (C)2015,JPO&INPIT【課題】芯線の先端部に外側と内側の二層構造のコイルを配した医療用ガイドワイヤにおいて、二層構造による芯線の細径化に伴い、先端側への回転伝達性能と、病変部の穿孔性能を向上させる。【解決手段】芯線先端部2Bは、第1,第2截頭円錐体26A,26Bを連接した連接截頭円錐体26を有している。内側コイル4と接合する連接截頭円錐体26の径大部と径小部の外径比を、内側コイル4の後端側と先端側の外径比、及び外側コイル3の後端側と先端側の外径比よりも高くする。回転操作時に手元側の回転角度を減少させ、かつ先端側へのねじりモーメントを増大させて、閉塞病変部の穿孔性能を向上させることができる。【選択図】図1