University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Peter Wipf,Athanassios Tzounopoulos
申请号：
US15526668
公开号：
US20180127357A1
申请日:
2015.11.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A compound, or pharmaceutically acceptable salt thereof, having a formula I of:wherein R1 is H or optionally-substituted alkyl；R2 is optionally-substituted alkyl；R3 and R4 are each independently H or optionally-substituted alkyl；R5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl；R6 and R7 are each independently H, deuterium, optionally-substituted alkyl, or R6 and R7 together form a carbocyclic；R8 is optionally-substituted thiazolyl, optionally-substituted thiophenyl, or substituted phenyl, provided that if R8 is 4-halophenyl, then R2 is substituted alkyl or branched alkyl or at least one of R6 or R7 is not H； andR30, R31 and R32 are each independently H, deuterium, halogen, substituted sulfanyl, or optionally-substituted alkoxy.
