The present invention provides in certain embodiments a method of suppressing pathological lymphatic formation in a tissue or organ in a mammal in need thereof comprising administering a therapeutic agent comprising Mir-184, pri-Mir-184, a Mir-184 mimic, or a vector comprising an expression cassette comprising a promoter and a nucleic acid encoding Mir-184, pri-Mir-184, or a Mir-184 mimic.
