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Protein a binding polypeptides, anti-EphA2 antibodies and methods of use thereof
专利权人:
Merrimack Pharmaceuticals, Inc.;The Regents of the University of California
发明人:
Drummond, Daryl,Marks, James D.,Geddie, Melissa,Kirpotin, Dmitri,Kohli, Neeraj,Lugovsky, Alexey
申请号:
AU2017234275
公开号:
AU2017234275A1
申请日:
2017.03.13
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Provided by the present disclosure are antibodies (e.g., scFvs) that include CDRs and human framework regions that confer useful properties upon the antibodies. In certain embodiments, such properties include thermostability (e.g., increased melting temperature), efficient binding to
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