ABSTRACT - 600267 The disclosure relates to an agent consisting of theobromine and an antihistamine as a combined preparation for use in a therapy of cough, wherein the agent is manufactured for administration by an oral route, wherein the antihistamine is selected from diphenhydramine, loratadine, desloratadine, alimemazine, dimenhydrinate, doxylamine, meclizine, quetiapine, fexofenadine, pheniramine, cetirizine, promethazine, clemastine, chlorpheniramine, dexchlorpheniramine, levocetirizine, hydroxyzine, alimemazine, acrivastine, cyproheptadine, astemizole, fexofenadine, loratadine, cetirizine, levocetirizine, brompheniramine, dextrobrompheniramine, promethazine, mizolastine, and triprolidine, and wherein the antihistamine, preferably chlorpheniramine, is to be administered in a dose of 0.1 to 30 mg/kg/day.
