And also provides a platelet production promoting factor novel able to effectively promote platelet formation or ER protrusion formation in megakaryocytes, using the platelet production promoting factor, an object of the present invention, a medicament useful The present invention is to provide various methods and compositions like. That is, the present invention provides plants comprising a higher concentration than in extracts of at least one microorganism plants not subjected to purification, and animals, a compound represented by the following general formula (1), a treated product thereof, or a composition of pharmaceutical products comprising said compound to said extract through the extract compound represented by the following general formula (1) preparation thereof to extract at least one of animal and microbial a treated product thereof, or a variety of methods using the compounds. [68] of本発明の目的は、巨核球系細胞における胞体突起形成又は血小板形成を効果的に促進することのできる新規な血小板産生促進因子を提供し、また、前記血小板産生促進因子を利用し、有用な医薬品等の組成物や各種方法を提供することにある。即ち本発明は、下記一般式(1)で示される化合物を、精製を行なっていない植物、動物、及び微生物の少なくともいずれかの抽出物における濃度よりも高濃度で含むことを特徴とする植物、動物、及び微生物の少なくともいずれかの抽出物乃至その処理物;下記一般式(1)で示される化合物;前記抽出物乃至その処理物、或いは前記化合物を含む医薬品等の組成物;前記抽出物乃至その処理物、或いは前記化合物を利用した各種方法である。【化68】