Préparation d'une forme solide de gadobénate diméglumine

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专利权人:

Bracco Imaging SPA

发明人:

申请号：

EP14178283.9

公开号：

EP2977369A1

申请日:

2014.07.24

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention relates to a process for the preparation of a solid form of the gadobenate dimeglumine compound that essentially comprises obtaining a solution of the said compound in a suitable solvent A and adding, under stirring and appropriate temperature conditions, the said obtained solution in a suitable organic solvent B, acting as an appropriate antisolvent and favoring the formation and precipitation of solid particles of the complex compound that can be easily collected by filtration in high yields and in a reliable way.

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