A micro-particle structure including a compound containing bitter melon, lemon verbena, and roselle for decreasing weight and body fat is provided in the disclosure. The micro-particle structure includes a core body and an exterior structure body. The exterior structure body from the inside thereof includes an encapsulation body and a protective layer. The encapsulation body encapsulates the core body. The protective layer has a membrane-shaped structure, encapsulating the encapsulation body. The micro-particle structure can decrease the accumulation of the fat. Besides, it can be added to any drinks or food ingredients, contributed to the property of the solubility in the water and the oil, and it can also maintain the activity of the nutrient composition it encapsulates.本新型提供一種具有降低體重及體脂肪功效的含有苦瓜、檸檬馬鞭草、洛神花複方的微粒結構,其包括核心體及外層結構體,該外層結構體由內而外依序包括包覆體及保護層,保護層係為膜狀構造,包覆核心體於內部。本新型之微粒構造具有減少脂肪累積之效。此外,還同時具有水溶性及油溶性之特性,可加入任何飲品或食材中使用,且不因消化液作用而降低所包覆之營養組合物之活性。。