The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans.本發明揭露關於含某些嘧啶化合物之組成物,例如敏諾西迪(minoxidil)及/或某些嘧啶硫酸鹽(分子內鹽)化合物,例如硫酸敏諾西迪(minoxidil sulfate),以及特別是含嘧啶化合物併以包含至少一抗氧化劑、至少一有機酸及一選定脂肪酸混合物之摻合物的組成物。本發明揭露亦關於使用該組成物使哺乳動物、特別是人類的毛髮生長及/或再生長毛髮及/或預防毛髮掉落。