Wentian Yang,Michael G. Ehrlich,Yi Zhou,Douglas Moore
申请号：
US14760413
公开号：
US20150352131A1
申请日:
2014.01.16
申请国别(地区):
US
年份:
2015
代理人:
摘要：
This application discloses compositions, devices, and methods for the prevention and treatment of osteolysis and osteoporosis. Treatment or prevention of osteolysis or osteoporosis is carried out by targeting the enzyme, Shp2 (a Src homology 2 (SH2) domain containing non-transmembrane Protein Tyrosine Phosphatase (PTP)), or proteins involved in the Shp2 signaling pathway by administering a Shp2 pathway inhibitor that inhibits fusion of pre-osteoclasts.
