SETO, Pui,BAEUERLE, Patrick,GUENOT, Jeanmarie,WESCHE, Holger,DUBRIDGE, Robert B.,LEMON, Bryan D.,AUSTIN, Richard J.
申请号：
EP17874048
公开号：
EP3544629A4
申请日:
2017.11.22
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Provided herein are prostate specific membrane antigen (PSMA) targeting trispecific proteins comprising a domain binding to CD3, a half-life extension domain, and a domain binding to PSMA. Also provided are pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such PSMA targeting trispecific proteins. Also disclosed are methods of using the disclosed PSMA targeting trispecific proteins in the prevention, and/or treatment diseases, conditions and disorders.
