The invention relates to the field of tissue engineering and regenerative medicine, and particularly to a three-dimensional biomimetic tissue scaffold that exploits the use of three-dimensional print technology. Surface energy is controlled by precisely placing polymers with differing surface chemistry, and using surface texture and bulk composition to pattern absorbable and non-absorbable polymers for the purpose of promoting functional healing in a mammalian body.本發明關於組織工程化及再生醫學之領域,特別是活用三維列印技術應用的三維仿生組織支架(three-dimensional biomimetic tissue scaffold)。藉由精確地配置具不同表面化學之聚合物,及利用表面紋理及整體組成將吸收性和非吸收性聚合物(non-absorbable polymer)圖案化來控制表面能,此係為了促進哺乳動物身體之機能復原的目的。302‧‧‧網格306‧‧‧中央部312‧‧‧第二層314‧‧‧圓315‧‧‧直徑316‧‧‧交叉點320‧‧‧第三層322‧‧‧線段324‧‧‧線段末端