用於治療膽道癌的標靶性TGF-B抑制之給藥方案农业专利-农业学术服务平台

发明人:: OSADA, MOTONOBU,长田元信,長田元信,EL BAWAB, SAMER,艾尔　巴瓦伯　沙曼,艾爾　巴瓦伯　沙曼,DUSSAULT, ISABELLE,杜沙特　伊莎贝尔,杜沙特　伊莎貝爾,VUGMEYSTER, YULIA,维格美斯特　优利亚,維格美斯特　優利亞,KHANDELWAL, AKASH,坎德瓦　阿卡许,坎德瓦　阿卡許,CHRISTENSEN, OLAF,克里史坦森　欧雷夫,克

摘要：: This disclosure relates to dosage regimens for targeted TGF-β inhibition with a bi-functional fusion protein for use in a method of treating biliary tract cancer or inhibiting biliary tract tumor growth in treatment naïve patients, or patients with locally advanced or metastatic BTC who have failed or are intolerant to first-line systemic chemotherapy.本發明係關於用雙功能融合蛋白標靶TGF-β抑制之給藥方案，用於治療膽道癌或抑制膽道腫瘤生長於初始(naïve)治療患者或一線全身化學療法失敗或不耐受的局部晚期或轉移性BTC之患者的方法中。