An use of the extraction of emblica officinalis in preparing pharmaceutical composition for protecting and repairing mitochondria includes providing an extraction of emblica officinalis. When the pharmaceutical composition is provided to a cell, the extraction of emblica officinalis improves the ability of performing the oxidative phosphorylation for the synthesis of the adenosine triphosphate (ATP) by mitochondria in the cell. The extraction of emblica officinalis also reduces the proton leakage of the mitochondria.一種餘甘子萃取物用於製備保護與修復粒線體的醫藥組合物之用途,包含提供餘甘子萃取物。當醫藥組合物被提供予一細胞時,餘甘子萃取物提高細胞內的複數個粒線體進行氧化磷酸化反應與三磷酸線苷(ATP)合成的能力,且餘甘子萃取物降低粒線體的氫離子洩漏。