Universitat Zurich;Charite Universitatsmedizin Berlin
发明人:
Becher, Burkhard,Heppner, Frank
申请号：
AU2012204869
公开号：
AU2012204869B2
申请日:
2012.01.04
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The invention provides antibody against p40, IL-12 or IL-23 for the prevention or treatment of Alzheimer's disease. It further provides ligands to the pair of interleukin 12 or 23 and its specific receptor, specifically an antibody, an antibody fragment, an antibody-like- molecule, for the prevention or treatment of Alzheimer's disease. Similarly, siRNA, antisense or transcription factor modulators of gene expression of p19, p35, p40, IL-12R- β1, IL-12R-β2, and/or IL-23R for the prevention or treatment of Alzheimer's disease are provided.
