MODULATORS OF IL-12 AND/OR IL-23 FOR THE PREVENTION OR TREATMENT OF ALZHEIMERS DISEASE

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专利权人:

发明人:

Burkhard Becher,Frank Heppner

申请号：

US15000063

公开号：

US20160207994A1

申请日:

2016.01.19

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The invention provides antibody against p40, IL-12 or IL-23 for the prevention or treatment of Alzheimers disease. It further provides ligands to the pair of interleukin 12 or 23 and its specific receptor, specifically an antibody, an antibody fragment, an antibody-like-molecule, for the prevention or treatment of Alzheimers disease. Similarly, siRNA, antisense or transcription factor modulators of gene expression of p19, p35, p40, IL-12R-β1, IL-12R-β2, and/or IL-23R for the prevention or treatment of Alzheimers disease are provided.

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