The present invention is a medicine, which is used to administer oxaliplatin intravenously to a human cancer patient and then stop the drug as a cycle of treatment and repeat the cycle to make peripheral nerves derived from oxaliplatin The symptoms of the disorder are alleviated and/or the onset is suppressed, and the medicine contains the effective thrombinmodulin for intravenous administration of 0.06 mg/kg of thrombinmodulin every 1 cycle on the first day of each cycle of treatment ingredient.本發明係一種醫藥，其係於將向人類癌症患者靜脈內投予奧沙利鉑並於其後停藥作為1週期並反覆該週期之治療中，用於使源自奧沙利鉑之末梢神經障礙之症狀減輕及/或發病抑制者，且該醫藥含有用以於治療之各週期之第一天每1週期靜脈內投予1次凝血酶調節素0.06 mg/kg的凝血酶調節素作為有效成分。
