PROBLEM TO BE SOLVED: To obtain an agent preventing/ameliorating foul mouth, dental caries and periodontoses-related diseases through preventing oral cavity pathogenic bacteria from deposition/setting on teeth surfaces by inhibiting their co-aggregation on the mucosa and teeth surfaces.SOLUTION: This co-aggregation inhibitor for Fusobacterium nucleatum bacteria and other oral cavity bacteria comprises mannitol or palatinite as active ingredient.COPYRIGHT: (C)2005,JPO&NCIPI【課題】 粘膜や歯面での口腔内細菌の共凝集を抑制することによって口腔内病原細菌の歯面への付着・定着を防止し、口臭、齲蝕、歯周病関連疾患を予防・改善する剤を提供する。【解決手段】 マンニトール又はパラチニットを有効成分とするフソバクテリウム ヌクレアタム属細菌と他の口腔内細菌との共凝集抑制剤。【選択図】なし
