LEE, SANG HYUN,이상현,CHO, EUN JU,조은주,CHOI, KYUNG,PARK, KWANG WOO,박광우,KU, JA JUNG,구자정
申请号：
KR1020120157208
公开号：
KR1020130077806A
申请日:
2012.12.28
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: An Ixeris polycephala Cassini extract, and urs-12-ene and olean-12-en-3-ol isolated from the extract are provided to ensure excellent antibacterial activity against gram-negative bacteria, gram-positive bacteria, or helicobacter pylori, and to be used as an antibacterial composition and a therapeutic agent for treating disease caused by bacteria.CONSTITUTION: An antibacterial pharmaceutical composition contains an Ixeris polycephala Cassini extract as an active ingredient. The extract is prepared using water, C1-C4 alcohols, or a mixture thereof. The extract has antibacterial activity against one or more microbes selected from the group consisting of helicobacter pylori, Staphylococcus aureus, and E.coli. The antibacterial pharmaceutical composition contains one or more compounds selected from the group consisting of chemical formulas 1 and 2, as active ingredients. The compounds are isolated from the extract.COPYRIGHT KIPO 2013본 발명은 벌씀바귀(Ixeris polycephala Cassini) 추출물 및 이로부터 분리한 활성물질을 유효성분으로 포함하는 항균 조성물에 관한 것이다. 본 발명에 따른 벌씀바귀 추출물 및 이로부터 분리한 울-12-엔 (urs-12-ene) 및 올레안-12-엔-3-올 (olean-12-en-3-ol)은 그람음성균, 그람양성균 또는 헬리코박터 파이로리균에 대한 우수한 항균 활성을 가지고 있어, 항균용 조성물 또는 상기 균주에 의해 발생하는 질병에 대한 치료제로 유용하게 이용될 수 있다.
