A device (30) for modifying conduction, electrical connection and propagation properties in a tissue comprising :a structural platform (30) made of a biocompatible materialthe platform (30) conformable to a shape of a target tissue site (36) having a vessel wall the platform (30) having a treatment component sized and shaped to induce a fibrotic response in the target tissue (36) and the treatment component being configured to cause sufficient fibrotic response so as to substantially eliminate the cardiac arrhythmias, wherein the device is configured to be radially expanded to overstretch the vessel wall so that the overstretching induce fibrosis in the tissue at the target tissue site (36).