BARDEY, Vincent,BONNET, Isabelle,ECHARD, Anabelle,PELLETIER, Nicolas,VOGELGESANG, Boris
申请号：
EP18728212.4
公开号：
EP3618802A1
申请日:
2018.05.03
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The invention relates to the use of various extracts of the Nephelium lappaceum plant for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes. Another subject of the invention relates to the use of said extracts in a cosmetic composition comprising at least one cosmetically acceptable excipient. Another subject further relates to a cosmetic care method comprising the application of the extract according to the invention or of a cosmetic composition comprising it, for increasing the firmness and/or elasticity of the skin and/or mucous membranes, by increasing type I and/or type V collagen, fibrillin-1 and/or LOX-L, fibulin-5, emiline-1 and/or fibrillin-1 gene and/or protein expression, and/or by decreasing CYR61 expression, in the skin and mucous membranes. A final subject relates to an N. lappaceum extract for use thereof, alone or in a dermatological or pharmaceutical composition, in the prevention and/or treatment of pathological conditions involving a loss of collagen protein and/or gene expression and/or a pathological loss of firmness of the skin and/or mucus membranes, such as rosacea and telangiectasia.L'invention concerne l'utilisation de différents extraits de la plante Nephelium lappaceum pour augmenter la fermeté et/ou l'élasticité de la peau et/ou des muqueuses, en augmentant l'expression génique et/ou protéique de collagène de type I et/ou V et/ou de LOX-L, de fibuline-5, d'Emiline-1 et/ou de fibrilline-1, et/ou en diminuant l'expression de CYR61, dans la peau et les muqueuses. Un autre objet de l'invention concerne l'utilisation desdits extraits dans une composition cosmétique comprenant au moins un excipient cosmétiquement acceptable. Un autre objet concerne encore un procédé de soin cosmétique comprenant l'application de l'ex
