Edith Mathiowitz,Solomon S. Steiner,Bryan E. Laulicht,Sasha Bakhru
申请号：
US14124040
公开号：
US20140120162A1
申请日:
2012.06.06
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Compositions containing one or more active agents, one or more bioadhesives elements, and one or more charge masking agents are described herein. In some embodiments, the one or more active agents are biomolecules or macromolecules, such as polysaccharides, proteins, peptides, or nucleic acids, which are charged at physiological pH. The one or more charge masking agents are selected based on the nature of the charge on the active agent. The compositions may also contain one or more controlled release materials, such as extended or sustained release materials or delayed release materials, in order to modify release of the active agent.
