The present invention relates to novel pyridines, their derivatives, pharmaceutically acceptable salts, solvates, entiomers, prodrugs and hydrates thereof. The compounds and compositions of the present invention have protein kinases inhibitory activities and are expected to be useful for the treatment of protein kinases mediated diseases and conditions, including hyper-proliferative disorder, ALK kinases mediated disorder, and neoplasia.本発明は、ピリジン、それらの誘導体、薬学的に許容される塩、溶媒和物、及び水和物に関する。本発明の化合物及び組成物は、プロテインキナーゼ阻害活性を有し、プロテインキナーゼ媒介疾患及び状態の治療に有用であると考えられる。【選択図】なし
