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DOSAGE FORM, AND METHODS FOR TREATING PROLIFERATIVE DISORDERS, AND FOR PREPARING THE DOSAGE
专利权人:
ABBOTT GMBH & CO. KG
发明人:
BERND LIEPOLD,JOERG ROSENBERG,MARTIN KNOBLOCH,CHRISTIAN NEHEN
申请号:
BRPI0718521
公开号:
BRPI0718521A2
申请日:
2007.11.08
申请国别(地区):
BR
年份:
2013
代理人:
摘要:
The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, (b) at least one polymeric binder, and (c) at least one pharmaceutically acceptable non-ionic surfactant. The invention provides imatinib dosage forms with high drug loading which can be prepared in a simple and efficient manner, imatinib dosage forms from which the active principle is released in an essentially pH-independent fashion, and extended release imatinib dosage forms.
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