The General Hospital Corporation DBA Massachusetts
发明人:
HOOKER, Jacob, M.,WANG, Changning,SCHROEDER, Frederick, Albert
申请号:
EP14853451
公开号:
EP3062783A4
申请日:
2014.10.17
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Disclosed herein are histone deacetylase imaging agents for positron emission tomography and related imaging methods using the histone deacetylase imaging agents. The histone deacetylase imaging agents may be a compound of formula (I): wherein R1 is a moiety including a positron emitter R2 represents hydrogen, or substituted or unsubstituted alkyl, or substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl and n is an integer selected from 0 or 1. In one version of the compound of formula (I), R1 is a moiety including an adamantyl group.