SPIRO-[1,3]-OXAZINES AND SPIRO-[1,4]-OXAZEPINES AS BACE1 AND/ORBACE2 INHIBITORS

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

NARQUIZIAN ROBERT,WOSTL WOLFGANG,PINARD EMMANUEL

申请号：

ZA201308395

公开号：

ZA201308395B

申请日:

2013.11.07

申请国别(地区):

ZA

年份:

2014

代理人:

摘要：

The present invention provides spiro-[1,3]-oxazines and spiro-[1,4]-oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.

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中国工程科技知识中心

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