Provided is an adhesive sheet for adhesion to the skin, which has sufficient adhesiveness and causes low skin irritation. Moreover, provided is a transdermal absorption preparation having, in addition to the above-mentioned property, sufficient drug releaseability.An adhesive sheet for adhesion to the skin, which comprises a support and an adhesive layer formed on the support, wherein the adhesive layer contains at least a thermoplastic elastomer, and a non-volatile hydrocarbon oil in an amount exceeding 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the thermoplastic elastomer is a mixture of a triblock copolymer and a diblock copolymer, wherein the content of the diblock copolymer in the mixture is not less than 20 wt%.
