PROBLEM TO BE SOLVED: To provide a therapeutic or preventive agent which shows good biokinetics in diseases, such as mood disorder, anxiety disorder, schizophrenia, Alzheimers disease, Parkinsons disease, Huntingtons chorea, eating disorder, hypertension, digestive system disease, drug dependence, epilepsy, cerebral infarction, brain ischemia, cerebral edema, head injury, inflammation, immune-associated diseases, and alopecia.SOLUTION: Provided is a therapeutic or preventive agent for disease of mood disorder, anxiety disorder, schizophrenia, Alzheimers disease, Parkinsons disease, Huntingtons chorea, eating disorder, hypertension, digestive system disease, drug dependence, epilepsy, cerebral infarction, brain ischemia, cerebral edema, head injury, inflammation, immune-associated diseases, and alopecia, containing as an active ingredient an azole derivative represented by the general formula (I) or a pharmaceutically acceptable salt thereof having an arginine vasopressin 1b receptor antagonism.COPYRIGHT: (C)2015,JPO&INPIT【課題】気分障害、不安障害、統合失調症、アルツハイマー病、パーキンソン病、ハンチントン舞踏病、摂食障害、高血圧、消化器疾患、薬物依存症、てんかん、脳梗塞、脳虚血、脳浮腫、頭部外傷、炎症、免疫関連疾患、脱毛症等の疾患において良好な体内動態を示す治療又は予防剤の提供。【解決手段】アルギニン-バソプレッシン1b受容体拮抗作用を有する、一般式(I)で表されるアゾール誘導体、又はその医薬上許容される塩を有効成分として含有する気分障害、不安障害、統合失調症、アルツハイマー病、パーキンソン病、ハンチントン舞踏病、摂食障害、高血圧、消化器疾患、薬物依存症、てんかん、脳梗塞、脳虚血、脳浮腫、頭部外傷、炎症、免疫関連疾患、脱毛症等の疾患の治療又は予防剤。【選択図】なし
