PROBLEM TO BE SOLVED: To provide a new therapeutic or preventive agent of diseases such as sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependence, Alzheimer disease, Parkinson disease, Huntington chorea, eating disorder, pain, migraine, gastrointestinal disease, epilepsy, inflammation, immunity related disease, endocrine related disease and hypertension.SOLUTION: A therapeutic or preventive agent of diseases such as sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependence, Alzheimer disease, Parkinson disease, Huntington chorea, eating disorder, pain, migraine, gastrointestinal disease, epilepsy, inflammation, immunity related disease, endocrine related disease and hypertension is characterized by containing a heteroaromatic ring derivative represented by the general formula (IA) having an ohlexin (OX) receptor antagonism or a pharmaceutically acceptable salt thereof as an active ingredient.COPYRIGHT: (C)2014,JPO&INPIT【課題】新規な睡眠障害、うつ病、不安障害、パニック障害、統合失調症、薬物依存症、アルツハイマー病、パーキンソン病、ハンチントン舞踏病、摂食障害、疼痛、片頭痛、消化器疾患、てんかん、炎症、免疫関連疾患、内分泌関連疾患、高血圧等の疾患の治療又は予防薬を提供すること。【解決手段】オレキシン(OX)受容体拮抗作用を有する一般式(IA)で表わされるヘテロ芳香環誘導体、又はその医薬上許容される塩を有効成分として含有することを特徴とする睡眠障害、うつ病、不安障害、パニック障害、統合失調症、薬物依存症、アルツハイマー病、パーキンソン病、ハンチントン舞踏病、摂食障害、疼痛、片頭痛、消化器疾患、てんかん、炎症、免疫関連疾患、内分泌関連疾患、高血圧等の疾患の治療又は予防薬。【化1】【選択図】なし
