Michael P. O'Neil,Leonard C. DeBenedictis,George Frangineas, JR.,Michael P. ONeil
申请号：
US15833329
公开号：
US20180185081A1
申请日:
2017.12.06
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.
