THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
AALIPOUR, AMIN,GAMBHIR, SANJIV S.
申请号:
CA3091799
公开号:
CA3091799A1
申请日:
2019.02.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Embodiments of genetically engineered immune cells are described herein which provide a new class of cell-based in vivo sensors useful for ultrasensitive disease detection based on the ability of immune cells to migrate to a site of pathology. The cell-based sensors provide an approach to early cancer detection and allow the use of the engineered immune cells in monitoring of diverse disease states including, but not limited to, cancer.