ANTICORPS BIFONCTIONNEL ANTI-CTLA4 ET ANTI-PD -1, COMPOSITION PHARMACEUTIQUE ET UTILISATION ASSOCIEES

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专利权人:

INC.;AKESO PHARMACEUTICALS

发明人:

LI, BAIYONG,XIA, YU,WANG, ZHONGMIN MAXWELL,ZHANG, PENG

申请号：

CA3034850

公开号：

CA3034850A1

申请日:

2017.08.22

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

An anti-CTLA4 (cytotoxic T lymphocyte associated antigen 4) and anti-PD-1 (programmed cell death 1) bifunctional antibody, a pharmaceutical composition thereof and use thereof. Particularly, the anti-CTLA4 and anti-PD-1 bifunctional antibody comprises a first protein functional domain that targets PD-I and a second protein functional domain that targets CTLA4. The bifunctional antibody can bind toCTLA4 and PD-1 specifically, relieve immunosuppression of CTLA4 and PD-1 on an organism specifically, activate T lymphocytes, and thus has good application prospects.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/