A book sterilizer is provided, which includes a sterilizing chamber having an upper wall, a lower wall, and an inclined rear wall between the upper and lower walls, and at least one holding member for a book which is provided in the sterilizing chamber and has a free end adjacent to the inclined rear wall, so that a book is easily held by virtue of having been inserted between the inclined rear wall and the holding member with the leaves and book covers separately opened such that they unfold under their own weight and gravity, so that upon spraying air, the book covers and the leaves of the book smoothly unfold and thus sterilizing rays from a sterilization and disinfection lamp are uniformly radiated deep into the book covers and the leaves, thereby providing excellent sterilizing effects at an economical cost.