The present invention relates to compounds of below Formula (I), physiologically functional derivatives or salts thereof, where the groups R1, R2, R3, R4, R<；SP>；A<；/SP>；, X1, and A, as well as the variables n, m and p are detailed further herein. In another aspect, the present invention provides methods for their preparation, their medical use and pharmaceutical compositions comprising said compounds, physiologically functional derivatives, solvates or salts thereof.本發明係關於下式(I)之化合物、其生理功能衍生物或鹽，其中基團R1、R2、R3、R4、RA、X1及A以及變量n、m及p在本文中進一步詳細闡述。□在另一態樣中，本發明提供其製備方法、其醫學用途及包含該等化合物、其生理功能衍生物、溶劑合物或鹽之醫藥組合物。
