TESTE Netan E.,KARRIGAN Kristina N.,EB Olga,TAVARES Deniel,VULF Beni B.
申请号:
RU20150104579
公开号:
RU2668824(C2)
申请日:
2013.08.30
申请国别(地区):
俄罗斯
年份:
2018
代理人:
摘要:
FIELD: pharmaceuticals.SUBSTANCE: present invention refers to immunology. Proposed is a antibody or antigen-binding fragment thereof that specifically binds to human shed folate receptor 1 (FOLR1). Also disclosed is a nucleic acid molecule, a method for detecting a FOLR1 protein in a sample, a cell and a method for producing an antibody or antigen-binding fragment thereof. In addition, an immunoassay kit for detecting FOLR1 protein in a sample is described.EFFECT: present invention can be used in the diagnosis and treatment of cancer.14 cl, 15 dwg, 6 tbl, 9 ex