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DIAGNOSTIC ASSAYS AND KITS FOR DETECTING PHOLATE RECEPTOR 1
专利权人:
ImmunoGen; Inc.
发明人:
TESTA, Nathan E.,AB, Olga,TAVARES, Daniel,WOLF, Beni B.,CARRIGAN, Christina N.
申请号:
DK13833526
公开号:
DK2890717T3
申请日:
2013.08.30
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1 -based therapies. Methods of using the antibodies to monitor therapy are further provided. The present invention provides methods for detection of FOLRI in a sample and can be used, for example, to stratify patients. Thus, in one embodiment, the invention provides a method of treating a patient having a folate receptor 1 -mediated disease comprising: (a) measuring the shed folate receptor 1 (FOLRI) expression level or FOLRI on a circuiting tumor cell (CTC) in a sample taken from a patient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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