The present application relates to aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[c]pyrrole, and octahydrocyclohepta[c]pyrrole derivatives of formula (I)wherein R1, R2, R3, R4, R5, A, Y1, Y2, and Y3are as defined in the specification. The present application also relates to compositions comprising such compounds, processes for making such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.本申請案係關於式(I)芳基-與雜芳基-稠合之十氫吡咯并一氮七圜、八氫氧七圜烯吡咯、八氫吡咯并硫氮七圜二氧化物、十氫環庚[c]吡咯及八氫環庚[c]吡咯衍生物其中R1,R2,R3,R4,R5,A,Y1,Y2及Y3均如本專利說明書中所定義。本申請案亦關於包含此種化合物之組合物，製造此種化合物之方法，及使用此種化合物與組合物治療疾病狀態之方法，以及確認此種化合物之方法。
