LIM, Ok Jae,KIM, Mun Kyung,LEE, Yun Jung,LEE, Jee Won,YANG, Woo Seok,KIM, Yu Young,KWON, Young Eun,CHOE, Seung Hyon
申请号：
SG11202004529X
公开号：
SG11202004529XA
申请日:
2018.11.16
申请国别(地区):
SG
年份:
2020
代理人:
摘要：
The present invention relates to a transformed human cell and a use thereof and, more particularly, to a cell transformed with a gene for coding an MHC I cell membrane receptor and an MHC II cell membrane receptor by using a gene expression suppressing system using a guide RNA, and a use thereof. Such a transformed cell can effectively exhibit the therapeutic effect of cells evenin vivo,and cannot be removed by anin vivoimmune response. Therefore, it is expected that a composition comprising the immunocyte as an active ingredient can be usefully used for the treatment of cancer, infectious diseases, degenerative diseases or immunological diseases.
