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CHEMICAL COMPOUNDS
专利权人:
PFIZER LIMITED
发明人:
KEVIN NEIL DACK,ROBERT MCKENZIE OWEN,DAVID CAMERON PRYDE
申请号:
US15777678
公开号:
US20180346470A1
申请日:
2016.11.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to pyrazolopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-1H-pyrazolo[3,4-c]pyridazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4 and R5 are as defined in the description. The pyrazolopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They may useful in the treatment of a number of conditions, including pain and epilepsy.
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