A thermostable composition with antiviral and antimicrobial activity is used as a biologically active component for the production of sanitary and hygienic products, as well as for protection against bacterial and viral infections. In particular, the thermostable composition is a lyophilized powder containing the following components per 1 g of the composition: recombinant interferon gamma human with the activity from 500,000 to 2,000,000 IU/g 0.03 to 0.12 mg； lysostaphin with the activity from 50 to 200 U/g 0.17 to 0.68 mg； methoxy polyethylene glycol 30-150 mg； sodium alginate 10-25 mg； sodium dihydrophosphate dihydrate 120-250 mg； citric acid 35-110 mg and remaining dextran. The thermostable composition can be used as a component of oral hygiene products, toothpastes, sanitary and hygiene articles, a clothes conditioner and condom lubricant and in a number of medicinal products and drugs.
