The present invention relates to a substance derived from a combination of plant materials of Rubia cordifolia, Symplocos racemosa, Acorus calamus, Coriandrum sativum, Citrus limon, and at least one pharmaceutically accepted excipient selected from the group consisting of surfactants, oils, waxes, thickening agents (gelling agent), emollients, preservatives, vehicles, perfumes and colorants, wherein, the proportion of each plant material with respect to other is 1:1 and the amount of said substance ranges between 0.1 and 20 wt%. The present invention also relates to a process for preparing a topical anti-acne formulation.
