Brian Volkman,Joshua Ziarek,Christopher Veldkamp,Francis Peterson
申请号:
US15874476
公开号:
US20180148490A1
申请日:
2018.01.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a CXCL121 peptide engineered to resist peptide-induced dimerization by maintaining steric repulsion of the chemokine helix, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.