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(2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS
专利权人:
AstraZeneca AB
发明人:
Lönn, Hans Roland,Connolly, Stephen,Swallow, Steven,Karlsson, Staffan P.O.,Aurell, Carl-Johan,Pontén, John Fritiof,Doyle, Kevin James,Van De Poël, Amanda Jane,Jones, Graham Peter,Watson, David Wyn,Mac
申请号:
AU2017200338
公开号:
AU2017200338A1
申请日:
2017.01.18
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2017200338A120170202.pdf#####ABSTRACT The present disclosure relates to certain (2S)-N- [(IS)-1 -cyano-2-phenylethyl] -1,4oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), 5 (Formula (I)) that inhibit dipeptidyl peptidase 1(DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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