Lönn Hans Roland,Connolly Stephen,Swallow Steven,Karlsson Staffan Po,Aurell Carl-Johan,Pontén John Fritiof,Doyle Kevin James,Van De Poël Amanda Jane,Jones Graham Peter,Watson David Wyn,Macritchie Jaqu
申请号:
NZ72206315
公开号:
NZ722063A
申请日:
2015.01.23
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4- oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), (Formula (I)) that inhibit dipeptidyl peptidase 1(DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.