CELLS FOR PRODUCING RECOMBINANT IDURONATE-2-SULFATASE

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专利权人:

Inc.;Shire Human Genetic Therapies

发明人:

Boldog, Ferenc,Heartlein, Mike

申请号：

AU2018200710

公开号：

AU2018200710B2

申请日:

2018.01.30

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

#$%^&*AU2018200710B220191114.pdf#####ABSTRACT The present invention provides, among other things, methods and compositions for production of recombinant 12S protein with improved potency and activity using cells co- express 12S and FGE protein. In some embodiments, cells according to the present invention are engineered to simultaneously over-express recombinant 12S and FGE proteins. Cells according to the invention are adaptable to various cell culture conditions. In some embodiments, cells of the present invention adaptable to a large-scale suspension serum- free culture.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/